![Loss of ribonuclease DIS3 hampers genome integrity in myeloma by disrupting DNA:RNA hybrid metabolism | The EMBO Journal Loss of ribonuclease DIS3 hampers genome integrity in myeloma by disrupting DNA:RNA hybrid metabolism | The EMBO Journal](https://www.embopress.org/cms/asset/cb42f080-1bc9-444b-ae56-a712875eabb4/embj2021108040-fig-0008-m.jpg)
Loss of ribonuclease DIS3 hampers genome integrity in myeloma by disrupting DNA:RNA hybrid metabolism | The EMBO Journal
![Noncoding RNA processing by DIS3 regulates chromosomal architecture and somatic hypermutation in B cells | Nature Genetics Noncoding RNA processing by DIS3 regulates chromosomal architecture and somatic hypermutation in B cells | Nature Genetics](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41588-020-00772-0/MediaObjects/41588_2020_772_Fig1_HTML.png)
Noncoding RNA processing by DIS3 regulates chromosomal architecture and somatic hypermutation in B cells | Nature Genetics
![DIS3 Rabbit anti-Human, Polyclonal, Bethyl Laboratories 100 μL; Unconjugated:Antibodies, | Fisher Scientific DIS3 Rabbit anti-Human, Polyclonal, Bethyl Laboratories 100 μL; Unconjugated:Antibodies, | Fisher Scientific](https://assets.fishersci.com/TFS-Assets/LSG/antibodies/DIS3-Antibody-WB-IP-Bethyl-Laboratories-A303-764A-1-20180803145406.jpg-650.jpg)
DIS3 Rabbit anti-Human, Polyclonal, Bethyl Laboratories 100 μL; Unconjugated:Antibodies, | Fisher Scientific
![Rapid Depletion of DIS3, EXOSC10, or XRN2 Reveals the Immediate Impact of Exoribonucleolysis on Nuclear RNA Metabolism and Transcriptional Control - ScienceDirect Rapid Depletion of DIS3, EXOSC10, or XRN2 Reveals the Immediate Impact of Exoribonucleolysis on Nuclear RNA Metabolism and Transcriptional Control - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S2211124719301743-fx1.jpg)
Rapid Depletion of DIS3, EXOSC10, or XRN2 Reveals the Immediate Impact of Exoribonucleolysis on Nuclear RNA Metabolism and Transcriptional Control - ScienceDirect
![Nuclear RNA Exosome at 3.1 Å Reveals Substrate Specificities, RNA Paths, and Allosteric Inhibition of Rrp44/Dis3 - ScienceDirect Nuclear RNA Exosome at 3.1 Å Reveals Substrate Specificities, RNA Paths, and Allosteric Inhibition of Rrp44/Dis3 - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S1097276516305901-fx1.jpg)
Nuclear RNA Exosome at 3.1 Å Reveals Substrate Specificities, RNA Paths, and Allosteric Inhibition of Rrp44/Dis3 - ScienceDirect
![RNA exosome ribonuclease DIS3 degrades Pou6f1 to promote mouse pre-implantation cell differentiation - ScienceDirect RNA exosome ribonuclease DIS3 degrades Pou6f1 to promote mouse pre-implantation cell differentiation - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S221112472300058X-fx1.jpg)
RNA exosome ribonuclease DIS3 degrades Pou6f1 to promote mouse pre-implantation cell differentiation - ScienceDirect
![Biomolecules | Free Full-Text | The 3' to 5' Exoribonuclease DIS3: From Structure and Mechanisms to Biological Functions and Role in Human Disease Biomolecules | Free Full-Text | The 3' to 5' Exoribonuclease DIS3: From Structure and Mechanisms to Biological Functions and Role in Human Disease](https://pub.mdpi-res.com/biomolecules/biomolecules-05-01515/article_deploy/html/images/biomolecules-05-01515-ag.png?1581018435)
Biomolecules | Free Full-Text | The 3' to 5' Exoribonuclease DIS3: From Structure and Mechanisms to Biological Functions and Role in Human Disease
RNA exosome ribonuclease DIS3 degrades Pou6f1 to promote mouse pre-implantation cell differentiation
![Biomolecules | Free Full-Text | The 3' to 5' Exoribonuclease DIS3: From Structure and Mechanisms to Biological Functions and Role in Human Disease Biomolecules | Free Full-Text | The 3' to 5' Exoribonuclease DIS3: From Structure and Mechanisms to Biological Functions and Role in Human Disease](https://www.mdpi.com/biomolecules/biomolecules-05-01515/article_deploy/html/images/biomolecules-05-01515-g003.png)
Biomolecules | Free Full-Text | The 3' to 5' Exoribonuclease DIS3: From Structure and Mechanisms to Biological Functions and Role in Human Disease
![The ribonuclease Dis3 is an essential regulator of the developmental transcriptome | BMC Genomics | Full Text The ribonuclease Dis3 is an essential regulator of the developmental transcriptome | BMC Genomics | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2F1471-2164-13-359/MediaObjects/12864_2012_Article_4135_Fig3_HTML.jpg)
The ribonuclease Dis3 is an essential regulator of the developmental transcriptome | BMC Genomics | Full Text
![Schematic structure of Dis3 and Dis3-like proteins in yeast and human... | Download Scientific Diagram Schematic structure of Dis3 and Dis3-like proteins in yeast and human... | Download Scientific Diagram](https://www.researchgate.net/publication/44657091/figure/fig1/AS:276792247111681@1443003823041/Schematic-structure-of-Dis3-and-Dis3-like-proteins-in-yeast-and-human-beings-Schematic.png)
Schematic structure of Dis3 and Dis3-like proteins in yeast and human... | Download Scientific Diagram
![Loss of ribonuclease DIS3 hampers genome integrity in myeloma by disrupting DNA:RNA hybrid metabolism | The EMBO Journal Loss of ribonuclease DIS3 hampers genome integrity in myeloma by disrupting DNA:RNA hybrid metabolism | The EMBO Journal](https://www.embopress.org/cms/asset/8368802c-831c-4b19-af64-5858d6a85355/embj2021108040-fig-0001-m.jpg)
Loss of ribonuclease DIS3 hampers genome integrity in myeloma by disrupting DNA:RNA hybrid metabolism | The EMBO Journal
![A single subunit, Dis3, is essentially responsible for yeast exosome core activity | Nature Structural & Molecular Biology A single subunit, Dis3, is essentially responsible for yeast exosome core activity | Nature Structural & Molecular Biology](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fnsmb1184/MediaObjects/41594_2007_Article_BFnsmb1184_Fig1_HTML.jpg)
A single subunit, Dis3, is essentially responsible for yeast exosome core activity | Nature Structural & Molecular Biology
DIS3 mutations in multiple myeloma impact the transcriptional signature and clinical outcome | Haematologica
![Biomolecules | Free Full-Text | The 3' to 5' Exoribonuclease DIS3: From Structure and Mechanisms to Biological Functions and Role in Human Disease Biomolecules | Free Full-Text | The 3' to 5' Exoribonuclease DIS3: From Structure and Mechanisms to Biological Functions and Role in Human Disease](https://www.mdpi.com/biomolecules/biomolecules-05-01515/article_deploy/html/images/biomolecules-05-01515-g004.png)